The APhA Complete Review for the FPGEE

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The APhA Complete Review for the FPGEE Info

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The APhA Complete Review for the FPGEE provides a comprehensive review of basic pharmaceutical principles (dosage forms, math, bio-pharmaceutics, kinetics, basic and parenteral compounding, among others); the basic medical sciences (chemistry, biochemistry, physiology, anatomy, pharmacology, microbiology, and immunology); social and administrative sciences (practice management, pharmacoeconomics, biostatistics, health care systems, etc.); and the clinical sciences (basic therapeutics, communication skills, etc.). These topics are all included in the Foreign Pharmacy Graduate Equivalency Examination. Graduates of foreign pharmacy schools must pass this examination before proceeding to the NAPLEX and licensure in the United States..

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Excitotoxins: The Taste That Kills

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Excitotoxins: The Taste That Kills Info

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Ex-ci'-to-tox-in: a substance added to foods and beverages that literally stimulates neurons to death, causing brain damage of varying degrees. Can be found in such ingredients as monosodium glutamate, aspartame (NutraSweet®), cysteine, hydrolyzed protein, and aspartic acid.

Citing over five hundred scientific studies, Excitotoxins explores the dangers of aspartame, MSG, and other substances added to our food. This is an electrifying and important book that should be available to every American consumer..

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Schaum's Outline of Principles of Accounting I, Fifth Edition (Schaum's Outlines)

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Schaum's Outline of Principles of Accounting I, Fifth Edition (Schaum's Outlines) Description

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Confused by accounting? Problem solved.

Schaum's Outline of Principles of Accounting I helps you understand basic accounting concepts and offer extra practice on topics such as debits, credits, the chart of accounts, the ledger, inventory measurement, net realizable value, recovery of bad debts, and methods for computing interest. Coverage also includes fixed assets, depreciation and scrap value, methods of depreciation, payroll, and payroll taxes.

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Student Workbook and Resource Guide for Core Concepts in Pharmacology

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Student Workbook and Resource Guide for Core Concepts in Pharmacology Info

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Excellent Condition... very light penciling.

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Principles and Practice of Clinical Research, Third Edition

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Principles and Practice of Clinical Research, Third Edition La revue

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The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.

• Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research
• Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research
• Delves into data management and addresses how to collect data and use it for discovery
• Contains valuable, up-to-date information on how to obtain funding from the federal government

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A Clinical Trials Manual From The Duke Clinical Research Institute: Lessons from a Horse Named Jim

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A Clinical Trials Manual From The Duke Clinical Research Institute: Lessons from a Horse Named Jim Description

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"The publication of the second edition of this manual comes at an important juncture in the history of clinical research. As advances in information technology make it possible to link individuals and groups in diverse locations in jointly seeking the answers to pressing global health problems, it is critically important to remain vigilant about moral and ethical safeguards for every patient enrolled in a trial. Those who study this manual will be well aware of how to ensure patient safety along with fiscal responsibility, trial efficiency, and research integrity."
—Robert Harrington, Professor of Medicine, Director, Duke Clinical Research Institute, Durham, North Carolina, USA

The Duke Clinical Research Institute (DCRI) is one of the world's leading academic clinical research organizations; its mission is to develop and share knowledge that improves the care of patients around the world through innovative clinical research. This concise handbook provides a practical "nuts and bolts" approach to the process of conducting clinical trials, identifying methods and techniques that can be replicated at other institutions and medical practices.

Designed for investigators, research coordinators, CRO personnel, students, and others who have a desire to learn about clinical trials, this manual begins with an overview of the historical framework of clinical research, and leads the reader through a discussion of safety concerns and resulting regulations. Topics include Good Clinical Practice, informed consent, management of subject safety and data, as well as monitoring and reporting adverse events.

Updated to reflect recent regulatory and clinical developments, the manual reviews the conduct of clinical trials research in an increasingly global context. This new edition has been further expanded to include:

• In-depth information on conducting clinical trials of medical devices and biologics
• The role and responsibilities of Institutional Review Boards, and
• Recent developments regarding subject privacy concerns and regulations.

Ethical documents such as the Belmont Report and the Declaration of Helsinki are reviewed in relation to all aspects of clinical research, with a discussion of how researchers should apply the principles outlined in these important documents. This graphically appealing and eminently readable manual also provides sample forms and worksheets to facilitate data management and regulatory record retention; these can be modified and adapted for use at investigative sites.

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Medical Dosage Calculations For Dummies

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Medical Dosage Calculations For Dummies Description

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Score your highest in a medical dosage calculations course

A recent shortage of nurses in a society with an aging population has triggered the demand for students to enter the field of medical study. A dosage calculations course is required for most students earning an applied science degree in nursing, pharmacology, or paramedic programs.

Medical Dosage Calculations For Dummies tracks a typical dosage calculations course and provides helpful content in an approachable and easy-to-understand format. Plus, you'll get examples of the various calculations made to determine the appropriate quantity of drug or solution that should be administered to patients.

• Calculating drug dosages utilizing ratio-proportion, formula, and dimensional analysis
• Systems of measurement, including metric and apothecary and other conversion equivalents for a global audience
• The ins and outs of the charting systems for MAR (Medicine Administration Records)

If you're one of the hundreds of thousands of students aspiring to enter the medical field, Medical Dosage Calculations For Dummies is your ticket for scoring your highest on exams.

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Guide to Federal Pharmacy Law, 8th Ed. (Reiss, Guide to Federal Pharmacy Law)

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Guide to Federal Pharmacy Law, 8th Ed. (Reiss, Guide to Federal Pharmacy Law) Description

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This BEST SELLER is a comprehensive, easy-to-study guide to current federal pharmacy law. It is designed to help you review the most important federal pharmacy statutes and regulations, including the newest changes in the Patient Protection and Affordable Health care Act of 2010, Labeling of prescription containers,Biologics Price Competition and Innovation Act,Women's Preventative Health Care Amendment of 2012,Medicaid Tamper-resistant Prescription Law, Risk Evaluation and Mitigation Strategy (REMS) program,and much more! This book is designed to assist candidates in preparing for pharmacy law examinations in all states. It also includes over 300 practice federal law questions and answers..

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Case Files Pharmacology, Third Edition (LANGE Case Files)

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Case Files Pharmacology, Third Edition (LANGE Case Files) Info

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REAL-LIFE CLINICAL CASES FOR THE BASIC SCIENCES AND USMLE STEP 1

Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. Case Files: Pharmacology provides 56 true-to-life clinical cases that illustrate essential concepts in pharmacology. Each case includes an easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, pharmacology pearls, and USMLE-style review questions. With Case Files, you'll learn instead of memorize.

• Learn from 56 high-yield cases, each with board-style questions
• Master key concepts with clinical pearls
• Polish your approach to clinical problems and to patient care
• Maximize your board scores with the proven Case Files system

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Motivational Interviewing for Health Care Professionals

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Motivational Interviewing for Health Care Professionals La revue

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Motivational interviewing has been shown to improve treatment adherence and outcomes, promote health behavior change, improve patient satisfaction with care, and increase retention rates in complex case management.

Motivational Interviewing for Health Care Professionals: A Sensible Approach presents a new way of teaching the theory and practice of motivational interviewing to health care professionals. The book illustrates how motivational interviewing effectively replaces everyday persuasive strategies and language habits that trigger resistance in patients. It addresses those aspects of motivational interviewing that typically pose problems for health care professionals such as how to share medical expertise while at the same time empowering the patient by maintaining his or her autonomy in the decision-making process. Using motivational interviewing skills will enable health care professionals to communicate with patients in a clear, concise, and structured way. Health care professionals in all practice settings will have a greater impact on improving patient outcomes by using the tools and skills in this book.

Key Features:
New theoretical description of motivational interviewing developed specifically for health care professionals
Practical, step-by-step approach to motivational interviewing
Over 35 health care professional/patient dialogues demonstrate motivational interviewing skills
Three case studies including comprehensive dialogues and analyses demonstrate effectiveness of motivational interviewing in health care
Links to vides of the case studies.

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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients

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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients Info

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"Smart, funny, clear, unflinching: Ben Goldacre is my hero." ―Mary Roach, author of Stiff, Spook, and Bonk

We like to imagine that medicine is based on evidence and the results of fair testing and clinical trials. In reality, those tests and trials are often profoundly flawed. We like to imagine that doctors who write prescriptions for everything from antidepressants to cancer drugs to heart medication are familiar with the research literature about these drugs, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by the pharmaceutical industry. We like to imagine that regulators have some code of ethics and let only effective drugs onto the market, when in reality they approve useless drugs, with data on side effects casually withheld from doctors and patients.
All these problems have been shielded from public scrutiny because they are too complex to capture in a sound bite. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale.
With Goldacre's characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system in need of regulation. This is the pharmaceutical industry as it has never been seen before.

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Mosby's 2016 Nursing Drug Reference, 29e (SKIDMORE NURSING DRUG REFERENCE)

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Mosby's 2016 Nursing Drug Reference, 29e (SKIDMORE NURSING DRUG REFERENCE) Info

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Choose the drug handbook trusted for nearly 30 years! The newest edition of a series that has been trusted by nurses for nearly 30 years, Mosby’s 2016 Nursing Drug Reference makes it easy to find the most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled ― including 20 new entries for drugs recently approved by the FDA. And no other drug guide places a higher emphasis on patient safety, with Black Box Warnings for dangerous adverse reactions, highlighting of common and life-threatening side effects, and Safety Alert icons for situations requiring special attention. From nursing pharmacology expert Linda Skidmore-Roth, this perennial bestseller proves there is a difference in drug guides.

• More than 5,000 generic and trade-name drugs are profiled, covering almost every drug you will administer in practice or in clinicals.
• Comprehensive drug monographs include generic names, Rx or OTC availability, pronunciations, U.S. and Canadian trade names, functional and chemical classification, controlled-substance schedule, do-not-confuse drugs, action, uses, unlabeled uses, dosages and routes, available forms, side effects, contraindications, precautions, pharmacokinetics, interactions (including drug/herb, drug/food and drug lab test), nursing considerations, and treatment of overdose. 
• Black Box Warnings provide alerts to dangerous or life-threatening adverse reactions. 
• Common and life-threatening side effects are organized by body system, showing signs to watch for during assessments.
• Safety Alert icon highlights the most critical interactions and side effects.
• A companion website includes updates with recently approved drugs, a full-color pill atlas, drug dosage calculators, herbal products, Canadian drug information, patient teaching guidelines, and more.
• Coverage of IV drug administration highlights dosage and IV administration instructions, including safety considerations and Y-site, syringe, and additive compatibilities.
• Complete pharmacokinetic information includes the mechanism and absorption of the drug as well as its action, duration, and excretion.
• Nursing Process steps are used as the framework for organizing all nursing care information.
• Full-color design highlights important information, and an alphabetical organization by generic name provides quick and easy access.
• Flexible, water-resistant cover provides durability in the clinical setting.

• 20 NEW monographs provide up-to-date content on newly released drugs.

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 3rd Edition

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 3rd Edition Info

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, Third Edition, is a primary textbook for a first course in pharmacology. It offers an integrated mechanism-based and systems-based approach, incorporating the cell biology, biochemistry, physiology, and pathophysiology of organ systems. The completely updated Third Edition features content reflecting current research findings, more than 400 full-color illustrations, Drug Summary Tables, and increased coverage of drug metabolism and the treatment of mycobacterial infections.

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Calculation of Medication Dosages: Practical Strategies to Ensure Safety and Accuracy

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Calculation of Medication Dosages: Practical Strategies to Ensure Safety and Accuracy Info

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This text equips nurses with the decision making skills to ensure that medication dosages are calculated correctly and administered safely. The book integrates critical thinking and decision making into the dosage calculation process and uses a realistic case study approach, with photos of nurses, patients, tablets, solutions, syringes, injectables, and drug labels. The formula method and ratio and proportion method are both presented for all problems, and a separate appendix explains the dimensional analysis method.

Tables of equivalents, formulas, and abbreviations used in medication orders appear on the inside cover. A pocket card with common measurements and conversions is included..

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NCLEX: Pharmacology for Nurses: 105 Nursing Practice Questions & Rationales to EASILY Crush the NCLEX! (Nursing Review Questions and RN Content Guide, ... Practitioner, Career Trainer Exam Prep)

Read NCLEX: Pharmacology for Nurses: 105 Nursing Practice Questions & Rationales to EASILY Crush the NCLEX! (Nursing Review Questions and RN Content Guide, ... Practitioner, Career Trainer Exam Prep) gratuitment. book online now. You also can download comics, magazine and also books. Get online NCLEX: Pharmacology for Nurses: 105 Nursing Practice Questions & Rationales to EASILY Crush the NCLEX! (Nursing Review Questions and RN Content Guide, ... Practitioner, Career Trainer Exam Prep) today.

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NCLEX: Pharmacology for Nurses: 105 Nursing Practice Questions & Rationales to EASILY Crush the NCLEX! (Nursing Review Questions and RN Content Guide, ... Practitioner, Career Trainer Exam Prep) Info

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Now You Can EASILY Crush The NCLEX!

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Medical Dosage Calculations: A Dimensional Analysis Approach

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Medical Dosage Calculations: A Dimensional Analysis Approach Description

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For courses in medical dosage calculation in departments of nursing, pharmacy, pre-med, pre-dental, and other health disciplines; and for courses covering dosage calculation in other programs, such as pharmacology, pediatrics and critical care.

The complete and user-friendly guide to safe drug dosage calculation
Fully revised for current practices and medication, Medical Dosage Calculations remains the field’s most complete, user-friendly and accessible drug calculation text and workbook. Using the dimensional analysis format it pioneered, students begin with simple arithmetic, progressing to the most complex drug calculations. As they develop mathematical skills for accurate dosage calculations, they also gain a thorough professional understanding of safe drug administration. Compared with competitors, our text contains deeper, more realistic problems, incorporating actual dosages and requiring real critical thinking.

For courses in medical dosage calculation in departments of nursing, pharmacy, pre-med, pre-dental, and other health disciplines; and for courses covering dosage calculation in other programs, such as pharmacology, pediatrics and critical care.

The complete and user-friendly guide to safe drug dosage calculation
Fully revised for current practices and medication, Medical Dosage Calculations remains the field’s most complete, user-friendly and accessible drug calculation text and workbook. Using the dimensional analysis format it pioneered, students begin with simple arithmetic, progressing to the most complex drug calculations. As they develop mathematical skills for accurate dosage calculations, they also gain a thorough professional understanding of safe drug administration. Compared with competitors, our text contains deeper, more realistic problems, incorporating actual dosages and requiring real critical thinking.

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Pharmacology: with STUDENT CONSULT Online Access

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Pharmacology: with STUDENT CONSULT Online Access Info

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Pharmacology, 4th Edition helps you master the "must-know" concepts in this subject and how they apply to everyday clinical problem solving and decision making. This concise yet comprehensive text clearly explains and illustrates challenging concepts and helps you retain the material - from course exams and the USMLE Step 1 right through to clinical practice.

• Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
• Quickly reference essential information thanks to abundant tables throughout, and drug classification boxes at the beginning of each chapter.
• See how pharmacology applies to practice with real-world case studies.
• Prepare for exams with self-assessment questions at the end of each chapter.
• Understand complex concepts visually with the aid of superb full-color illustrations.
• Access the complete contents online at www.studentconsult.com, along with an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style questions, animations, and more.

• Learn the latest pharmacologic mechanisms and applications with new and updated drug information throughout.
• Be aware of new "off label" uses, including important FDA regulations.

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Dosage Calculations, 9th edition

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Dosage Calculations, 9th edition Info

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Best-selling DOSAGE CALCULATIONS, 9th Edition features the three-step approach to basic and advanced Formula Method calculations that nursing and other health care professionals prefer, along with a reader-friendly writing style and handy "work text" format. In addition to easing readers into the math with a thorough review, the book uses a logic-based process to build confidence and limit anxiety. Featuring full-color images of drug labels, critical thinking assessments, extensive clinical examples, and a host of interactive supplements, including an accompanying online tutorial, DOSAGE CALCULATIONS, 9th Edition provides the skills needed to master dosage calculations in any clinical setting!.

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Pharmacology: Principles and Applications

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Pharmacology: Principles and Applications La revue

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Comprehensive yet easy to read, Pharmacology: Principles and Applications, 3rd Edition introduces you to basic pharmacology, showing how to apply principles to the kinds of clinical situations you will encounter on the job. You'll learn how different drugs work in the body, how to calculate drug dosages, drug administration routes and procedures, the medications related to disorders in each body system, and much more. Written by expert authors Eugenia M. Fulcher, Robert M. Fulcher, and Cathy Dubeansky Soto, Pharmacology ensures that you master all of the pharmacology competencies required by CAAHEP and ABHES. In the book and on a companion Evolve website, a variety of exercises helps you strengthen your skills in math, dosage calculation, and critical thinking.

• Practical coverage of basic pharmacology provides a thorough understanding of the medications most commonly used in ambulatory and inpatient settings.
• A real-life Scenario starts each chapter with thought-provoking questions to consider as you progress through the material.
• Procedures boxes provide step-by-step guidance for drug calculation and administration, accompanied by numerous illustrations and icons that identify OSHA-mandated protocols.
• Common Signs & Symptoms of Diseases and Common Side Effects of Medications lists in each body system chapter help you distinguish between disease progression and medication reactions.
• Body systems icons highlight the ways that specific drugs affect a particular body system.
• Chapter objectives and key words at the beginning of each chapter help you focus your study efforts.
• Check Your Understanding math review sections enable you to assess your knowledge of application and calculation concepts.
• Critical Thinking exercises challenge you to apply what you've learned to a variety of realistic situations.
• Important Facts and Clinical Tips boxes in each chapter highlight the key concepts for practice.
• Patient Education for Compliance boxes help you communicate more effectively with patients about possible side effects or adverse reactions.

• Summary tables are more concise and easier to follow.
• New calculations exercises and quizzes are included on the companion Evolve website.
• Expanded math and drug calculation sections in the workbook supplement the textbook with additional exercises for practice with math and dosage calculations. Available separately.

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Pathophysiology: A Clinical Approach

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Pathophysiology: A Clinical Approach Info

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The Second Edition of Pathophysiology offers a unique clinical approach that facilitates learning by viewing pathophysiology as health care professionals do. Whereas a traditional systems-based approach impractically isolates diseases to a single body system, this textbook's approach recognizes how disease affects multiple systems. Additionally, rather than covering only a limited number of diseases, aiming for rote memorization of the key factors in those diseases, the clinical approach details the mechanisms of disease. By mastering the core concepts of altered human function, students can apply a deeper understanding to a host of diseases, rather than trying to memorize facts about specific conditions. Because students learn through application, they learn to think about pathophysiology the way they will need to in a clinical setting, by working from symptoms to the cause, rather than the other way around. Each chapter discusses clinical models, enhancing the real-world application of the material..

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Fundamental Skills For Patient Care In Pharmacy Practice

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Fundamental Skills For Patient Care In Pharmacy Practice Description

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Fundamental Skills for Patient Care in Pharmacy Practice enables students and new pharmacists to master the skills associated with clinical care in either the inpatient or outpatient setting. In accessible steps, this valuable resource provides the tools for gaining medication histories from patients and counseling them on the most effective and safe manner to take medications. Each chapter explores the background and practice of a critical skill, tools that aid in its development and mastery, and tips for success. Students and pharmacists will come away with the knowledge to identify drug-related problems and formulate plans for solutions to these problems. Fundamental Skills for Patient Care in Pharmacy Practice prepares future pharmacists to communicate effectively in verbal and written formats with health professionals and special patient populations as they prepare and present SOAP notes, patient cases, and discharge counseling..

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Pharmacology, 4e

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Pharmacology, 4e Info

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Pharmacology, 4th Edition helps you master the "must-know" concepts in this subject and how they apply to everyday clinical problem solving and decision making. This concise yet comprehensive text clearly explains and illustrates challenging concepts and helps you retain the material - from course exams and the USMLE Step 1 right through to clinical practice.

• Quickly reference essential information thanks to abundant tables throughout, and drug classification boxes at the beginning of each chapter.
• See how pharmacology applies to practice with real-world case studies.
• Prepare for exams with self-assessment questions at the end of each chapter.
• Understand complex concepts visually with the aid of superb full-color illustrations.
• Access the complete contents online at www.studentconsult.com, along with an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style questions, animations, and more.

• Learn the latest pharmacologic mechanisms and applications with new and updated drug information throughout.
• Be aware of new "off label" uses, including important FDA regulations.

.

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Cobert's Manual of Drug Safety and Pharmacovigilance

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Cobert's Manual of Drug Safety and Pharmacovigilance Info

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Completely revised and updated, the Manual of Drug Safety and Pharmacovigilance, Second Edition is a how-to manual for those working in the fields of drug safety, clinical research, pharmacology, regulatory affairs, government and legal professions. This comprehensive and practical guide discusses the theory and the practicalities of drug safety (also known as pharmacovigilance) and side effects, as well as providing essential information on drug safety and regulations, including: recognizing, monitoring, reporting and cataloging serious adverse drug reactions.

The Manual of Drug Safety and Pharmacovigilance, Second Edition teaches the ins and outs of drug safety in the industry, hospitals, FDA, and other health agencies both in the US and around the world, and presents critical information about what is done when confronted with a drug safety problem.

Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition..

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy Description

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Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets. Chapters are integrated into sections that focus on organ systems and therapeutic areas of highest importance. Clear, concise illustrations highlight key points, and drug summary tables offer quick access to essential information.

The Fourth Edition features:

• Comprehensive updates to all chapters, including recently approved drugs
• Nearly 40 popular and practical Drug Summary Tables with state-of-the-art information on clinical applications, serious and common adverse effects, contraindications, and therapeutic considerations
• A new chapter on drug transporters, and extensively revised information on drug-receptor interactions, pharmacodynamics, drug toxicity, and pharmacogenomics
• Key changes to Section 1: Fundamental Principles of Pharmacology, which now provides a comprehensive framework for material in all subsequent chapters
• Hundreds of meticulously updated and colorized illustrations, including many that are new or substantially modified to highlight new understanding of physiologic, pathophysiologic, and pharmacologic mechanisms

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