Excitotoxins: The Taste That Kills

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Excitotoxins: The Taste That Kills Info

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Ex-ci'-to-tox-in: a substance added to foods and beverages that literally stimulates neurons to death, causing brain damage of varying degrees. Can be found in such ingredients as monosodium glutamate, aspartame (NutraSweet®), cysteine, hydrolyzed protein, and aspartic acid.

Citing over five hundred scientific studies, Excitotoxins explores the dangers of aspartame, MSG, and other substances added to our food. This is an electrifying and important book that should be available to every American consumer..

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Chemical Dependency Counseling: A Practical Guide

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Chemical Dependency Counseling: A Practical Guide Info

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Chemical Dependency Counseling is a best-selling comprehensive guide for counselors and front-line professionals who work with the chemically dependent and addicted in a variety of treatment settings. The text shows the counselor how to use the best evidence-based treatments available, including motivational enhancement, cognitive behavioral therapy, skills training, medication and 12 step facilitation. Guiding the counselor step-by-step through treatment, this volume presents state-of-the-art tools, and forms and tests necessary to deliver outstanding treatment and to meet the highest standards demanded by accrediting bodies..

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The Medical Marijuana Dispensary: Understanding, Medicating, and Cooking with Cannabis

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The Medical Marijuana Dispensary: Understanding, Medicating, and Cooking with Cannabis Info

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Award-winning owners of the cannabis company Laurie & MaryJane bring their expertise to this reliable, at-your-fingertips resource for understanding the therapeutic effects of marijuana. 

Featuring a Foreword by Paul Armentano, Deputy Director of NORML

Part reference, part cannabis cookbook, The Medical Marijuana Dispensary provides up-to-date, evidence-based information and research supported by medical professionals, established experts, and members of the medical marijuana community.

Authors Laurie and Mary expertly guide beginners through the three easy-to-navigate sections of this primer for new patients. In Parts One and Two, they offer an in-depth overview of the history of medical marijuana and profiles of common cannabis strains (sativa, indica, hybrid). 

In Part Three, you’ll explore a range of easy-to-prepare edibles and effective remedies—from savory dishes to sweet treats to soothing tinctures and oils—with dosages that can easily be altered to suit your health needs.

Packed with useful cannabis resources, including an in-depth glossary, medical cannabis guidelines, a well-organized index listing ailments, symptoms and conditions, real-world patient testimonials, and tips for cultivating cannabis at home, The Medical Marijuana Dispensary is your accessible and informed guide to the world of medical marijuana.

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Pharmacology: An Introduction

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Pharmacology: An Introduction Info

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Pharmacology, 7e by Hitner/Nagle is incredibly readable, with short chapters that link theory to practice; content that is focused on the need-to-know information to not overload the reader; excellent tables and features such as Patient Administration and Monitoring Boxes; and the most up-to-date drug information. This new edition features revised Learning Outcomes for each chapter, with a more streamlined chapter structure to reflect those updates. Chapter reviews have been revisited to more closely mirror typical exam formats, and a variety of additional exercises are available on Connect Plus. The full suite of instructor materials is available. Hitner 7e has Connect Plus, including LearnSmart: Pharmacology, SmartBook, body system and pharmacology animations, dosage calculations exercises, and more..

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The Organic Chemistry of Drug Design and Drug Action, Third Edition

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The Organic Chemistry of Drug Design and Drug Action, Third Edition La revue

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The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.

New to this edition:

• Updates to all chapters, including new examples and references
• Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book
• Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry
• Chapter 3 (Receptors): Drug-receptor interactions, cation-π and halogen bonding; atropisomers; case history of the insomnia drug suvorexant
• Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis
• Chapter 5 (Enzyme Inhibition and Inactivation): New case histories:
• for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib
• for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid
• for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin
• Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples
• Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites
• Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

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FDA Regulatory Affairs: Third Edition

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FDA Regulatory Affairs: Third Edition La revue

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FDA Regulatory Affairs is a roadmap to prescription drug, biologics, and medical device development in the United States. Written in plain English, the concise and jargon-free text demystifies the inner workings of the US Food and Drug Administration (FDA) and facilitates an understanding of how the agency operates with respect to compliance and product approval, including clinical trial exemptions, fast track status, advisory committee procedures, and more.

The Third Edition of this highly successful publication:

• Examines the harmonization of the US Federal Food, Drug, and Cosmetic Act with international regulations on human drug, biologics and device development, research, manufacturing, and marketing
• Includes contributions from experts at organizations such as the FDA, National Institutes of Health (NIH), and PAREXEL
• Focuses on the new drug application (NDA) process, cGMPs, GCPs, quality system compliance, and corresponding documentation requirements
• Provides updates to the FDA Safety and Innovation Act (FDASIA), incorporating pediatric guidelines and follow-on biologics regulations from the 2012 Prescription Drug User Fee Act (PDUFA) V
• Explains current FDA inspection processes, enforcement options, and how to handle FDA meetings and required submissions

Co-edited by an industry leader (Mantus) and a respected academic (Pisano), FDA Regulatory Affairs, Third Edition delivers a compilation of the selected US laws and regulations as well as a straightforward commentary on the FDA product approval process that’s broadly useful to both business and academia.

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Pathophysiology: A Clinical Approach

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Pathophysiology: A Clinical Approach Info

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The Second Edition of Pathophysiology offers a unique clinical approach that facilitates learning by viewing pathophysiology as health care professionals do. Whereas a traditional systems-based approach impractically isolates diseases to a single body system, this textbook's approach recognizes how disease affects multiple systems. Additionally, rather than covering only a limited number of diseases, aiming for rote memorization of the key factors in those diseases, the clinical approach details the mechanisms of disease. By mastering the core concepts of altered human function, students can apply a deeper understanding to a host of diseases, rather than trying to memorize facts about specific conditions. Because students learn through application, they learn to think about pathophysiology the way they will need to in a clinical setting, by working from symptoms to the cause, rather than the other way around. Each chapter discusses clinical models, enhancing the real-world application of the material.

 

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